Current Ear Institute Job Vacancies
The UCL Ear Institute provides state-of-the-art research facilities across a wide range of disciplines including the study of the auditory system function and associated technologies, the molecular and cellular basis of hearing and the genetics of hearing and deafness. If you wish to join the Ear Institute, the following positions are currently available:
Applications are invited for a 3-year PhD studentship commencing September 25th 2014, funded by Action on Hearing Loss, UK. The studentship provides a tax-free stipend (£17,000 increasing annually by £500 to £18,000 in year 3) in addition to covering tuition fees at the UK/EU rate.
The neurobiology of acoustic trauma, one of the major causes of deafness and tinnitus in humans, is only poorly understood. Most of the molecular and cellular events triggered by the exposure to damagingly high sound levels are still unknown. To identify, characterize and quantify the effects of acoustic trauma on distinct stages of the auditory chain, this PhD project will apply, and extend, a recently devised Drosophila acoustic trauma/NIHL model (see Christie et al 2013). In this project the student will use a number of different techniques, including laser vibrometry, electrophysiological recording, confocal imaging, electron microscopy and computational biomechanics to investigate the effect of acoustic trauma on the fly’s hearing organ. A particular focus will be on the effects of trauma on mechanotransduction in different sensory cell types within the fly’s antennal ear; on sensory cell processing and signal transformation; on intracellular calcium signals in neurons and support cells and on mitochondrial function. There is also the potential to test the efficacy of various transgenic intervention techniques (e.g. adult-specific RNAi- or micro-RNA- mediated gene knockdown) to prevent, or accelerate, noise-induced hearing loss.
The UCL Ear Institute (http://www.ucl.ac.uk/ear) opened in 2005. It is one of the world’s leading research centres studying all aspects of hearing and deafness. It contains state-of-the-art facilities required for excellent research.
Successful applicants are expected to have a proven track record of academic excellence, having or expecting to obtain at least an upper second class Honours degree or a Master’s degree (Merit or Distinction) in a relevant subject. Prior knowledge in Drosophila neurobiology will be of advantage but is no requirement. Priority will be given to academic excellence.
Due to funding restrictions the post is only open to UK/EU citizens.
How to apply
- Informal enquiries and formal applications should be directed to firstname.lastname@example.org.
- Formal applications should include a CV (including a list of referees) and a covering letter outlining the motivation, interest and suitability for the project.
- Early applications are advisable.
date for applications is 1 May 2014 (Interviews to take place in June)
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Christie KW, Sivan-Loukianova E, Smith WC, Aldrich BT, Schon MA, Roy M, Lear BC, Eberl DF (2013) Physiological, anatomical, and behavioral changes after acoustic trauma in Drosophila melanogaster. P Natl Acad Sci USA 110:15449-15454
Page last modified on 02 aug 12 11:58