Dr. Dmitry Laptev

Dmitry's work deals with the computational modelling of spatial and episodic memory. A variety of different types of instability has been found in the saccadic system of humans. Some of the instabilities correspond to clinical conditions, whereas others are inherent in the normal saccadic system. How can these instabilities arise within the mechanism of normal saccadic eye movements?

Dmitry developed a physiologically-based model of the saccadic system which predicts that horizontal saccadic oscillations will occur with excessive mutual inhibition between the left and right burst cells and with underaction of the pause cells. The amplitudes and frequencies of the oscillations had ranges of 0–6° and 6–20 cycles per second, respectively. Application of stability analysis techniques to the model revealed that development of the oscillations could be explained by the Hopf bifurcation mechanism. Future development of Dmitry’s approach will involve classifying pathological instabilities of the saccadic system according to the bifurcation involved in their generation.

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