dr dave spratt
Research
Themes
Contacts
- Dr
- Dave
- Alexander
- Spratt
- Dr Dave Spratt
- Tel: 020 34561107
- Ex: 020 3456 1107
- Fax: 020 34561127
- d.spratt@ucl.ac.uk
- Website
- https://iris.ucl.ac.uk/iris/extResource/image/01/DASPR40
- 1997-08-26
Address
- 999
- -
- Microbial Diseases, UCL Eastman Dental Institute
- 256 Gray's Inn Rd
- London
- WC1X 8LD
Appointment
- ACARDR
- 1999-08-01
- 1
- Reader in Microbial Ecology
- Faculty Graduate Tutor
- IDR
- Microbial Diseases
- ID
- Eastman Dental Institute
Joined UCL
- 1997-08-26
Research Summary
At present my research activities revolve around a number of aspects of microbial ecology. I am primarily interested in understanding population shifts in our commensal microbiota which are associated with the inception and progression of polymicrobial diseases. A number of molecular techniques including metagenomics are now available which allow the population profile of a given microbial population to be ascertained in a unbiased and cultured independent manner. These techniques have revolutionised our understanding of the human microbiome and it is thought that perhaps 50,000 different species make up th ehuman microbiome.Research Activities
- 810
- Bacterial Biofilms and Ecology
- 6058
- Development of new injectable adhesive composites for bone repair
- 813
- Injectable drug - releasing composites for tooth a
- 6057
- Re-mineralising, antibacterial composites and adhesives for more durable, conservative and pain less tooth restoration
1 - 10 of 150 Publications
Identification of bacteria and potential sources in neonates at risk of infection delivered by Caesarean and vaginal birth
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Effects of mushroom and chicory extracts on the physiology and shape of Prevotella intermedia, a periodontopathogenic bacterium.
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Levels of periodontal pathogens in neonatal gastric aspirates and possible maternal sites of origin.
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Testing a low molecular mass fraction of a mushroom (Lentinus edodes) extract formulated as an oral rinse in a cohort of volunteers.
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The effects of fractions from shiitake mushroom on composition and cariogenicity of dental plaque microcosms in an in vitro caries model.
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In vitro assessment of shiitake mushroom (Lentinula edodes) extract for its antigingivitis activity.
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Drinking habits are associated with changes in the dental plaque microbial community
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Development of a novel multi-triplex qPCR method for the assessment of bacterial community structure in oral populations
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Publisher: WILEY-BLACKWELL PUBLISHING, INC
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Additional Information
- Biofilms
- Diabetes
- Fluorescence microscopy techniques
- Infection
- Infectious diseases
- Metabolomics
- Microspectroscopy
- Mixed methods: Qualitative & Quantitative
- Modelling
- Models of disease
- Mouth
- Oral
- Oral health
- Oral microbiology
- QPCR
- Raman
Collaborators
- JRPRA52
- dr jonathan pratten
- JCKNO52
- prof jonathan knowles
- VSALI04
- dr vehid salih
- AYOUN32
- dr anne young
- PASHL72
- dr paul ashley
- IPPAR53
- prof ivan parkin
- LBOZE75
- dr laurent bozec
External Collaborators
- 2483
- Juha-Pekka Nuutinen

