Dr Celia Morgan

 

Dr Celia Morgan


Lecturer


Telephone : 0207 679 1932

 

My research interests include

  • Drug abuse and its effects on cognition and psychopathology.
  • Psychopharmacological models of mental illness, in particular the acute ketamine model of schizophrenia.
  • Schizotypy and schizophrenia.

Internal Collaborators

Professor Val Curran

Dr. Oliver Mason

Professor Eileen Joyce

Professor Karl Friston

Dr. Jon Roiser

External Collaborators

Dr. Paul Fletcher

Dr. Phil Corlett

Dr. Susan Rossell

Dr. James Stone

Dr. Ed Roberts

Prof. David Nutt

The Beckley Foundation

Current projects

  • The determinants and consequences of ketamine use
  • Neuroanatomical and functional changes following daily ketamine use
  • Prodromal symptoms of schizophrenia, cognition and drug abuse
  • Cannabis and cognitive function
  • National drug survey: users views on the harms associated with psychoactive substance use

Recent and current grants

  • 2008 Curran HV & Morgan CJA. AERC.The acute effects of alcohol on prospective memory and related executive functions.
  • 2008-2012 Curran HV & Morgan CJA. MRC. What determines an individual's vunerability to the harmful effects of cannabis?
  • 2009-2011 Kamboj SK, Morgan, CJA & Curran HV. MRC. Exploring the potential of D-Cycloserine and cannabidiol to enhance cue exposure therapies in substance dependence.
  • 2010-2011 Morgan CJA. ECNP: European College of Neuropsychopharmacology Young Scientists Research Grant: The endocannabinoid system and cannabis dependence.

Publications

Morgan CJ
, Gardener C, Schafer G, Swan S, Demarchi C, Freeman TP, Warrington P, Rupasinghe I, Ramoutar A, Tan N, Wingham G, Lewis S, Curran HV, (in press) Sub-chronic impact of cannabinoids in street cannabis on cognition, psychotic-like symptoms and psychological well-being. Psychological Medicine.

Morgan CJ and Curran HV (in press). Ketamine use: a review. Addiction.

Freeman TP, Morgan CJA, Beesley T, Curran HV (in press). Drug-cue induced overshadowing: selective disruption of natural reward processing by cigarette cues amongst abstinent but not satiated smokers. Psychological Medicine.

Kamboj SK, Massey-Chase R, Rodney L, Das R, Almahdi B, Curran H, Morgan CJ (in press) Changes in cue reactivity and attentional bias following experimental cue exposure and response prevention: a laboratory study of the effects of D-cycloserine in heavy drinkers. Psychopharmacology.

Carroll EM, Kamboj SK, Conroy L, Tookman A, Williams AC, Jones L, Morgan CJ, Curran HV (2011) Facial Affect Processing in Patients Receiving Opioid Treatment in Palliative Care: Preferential Processing of Threat in Pain Catastrophizers. J Pain Symptom Manage, 41, 975-985.

Curran HV, Freeman TP, Schafer GL, Morgan CJA (2010) Does cannabidiol protect against the harms of THC? British Journal of Psychiatry.

Platt B, Kamboj S, Morgan CJA, Curran HV (2010) Processing dynamic facial affect in frequent cannabis-users: Evidence of deficits in the speed of identifying emotional expressions. Drug and Alcohol Dependence, 112, 27-32.

Morgan CJA, Schafer G, Freeman TP, Curran HV (2010) Impact of cannabidiol on the acute memory and psychotomimetic effects of smoked cannabis: a naturalistic study. British Journal of Psychiatry, 197, 285-90.

Morgan CJA
, Freeman TP, Schafer GL, Curran HV (2010) Cannabidiol Attenuates the Appetitive Effects of Delta(9)-Tetrahydrocannabinol in Humans Smoking Their Chosen Cannabis. Neuropsychopharmacology, 35, 1879-85.

Constantinou N, Morgan CJA, Battista S, O'Ryan D, Davis P, Curran HV (2010) Attentional bias, inhibitory control and acute stress in current and former opiate addicts. Drug and Alcohol Dependence, 109, 220-5.

Morgan CJA, Muetzelfeldt L, Muetzelfeldt M, Nutt DJ, Curran HV (2010) Harms associated with psychoactive substances: findings of the UK National Drug Survey. Journal of Psychopharmacology,24, 147-153.

Morgan CJA, Rothwell E, Atkinson H, Mason O, Curran HV (2010) Hyper-priming in cannabis users: a naturalistic study of the effects of cannabis on semantic memory function. Psychiatry Research, 176, 231-8.

Paraskevaides T, Morgan CJA, Leitz JR, Bisby JA, Rendell PG, Curran HV (2010) Drinking and future thinking: acute effects of alcohol on prospective memory and future simulation. Psychopharmacology, 208, 301-308.

Morgan CJA, Muetzelfeldt L, Curran HV (2010) Consequences of chronic ketamine self-administration upon neurocognitive function and psychological well-being: a 1 year longitudinal study. Addiction, 105, 121-133.

Bisby JA, Leitz JR, Morgan CJA, Curran, HV (2010) Decreases in recollective experience following acute alcohol: a dose-response study. Psychopharmacology, 208, 67-74.

Freeman TP, Morgan CJA, Klaasen E, Das RK, Stefanovic A, Brandner B, Curran HV (2009) Superstitious conditioning as a model of delusion formation following chronic but not acute ketamine in humans. Psychopharmacology, 206, 563-573.

Leitz JR, Morgan CJA, Bisby JA, Rendell PG, Curran HV (2009) Global impairments of Prospective Memory following Acute Alcohol. Psychopharmacology, 205, 379-387.

Morgan CJA, Huddy VJ, Baker M, Curran HV, Joyce EM (2009) Is persistent ketamine use a valid model of cognitive and oculomotor deficits in schizophrenia? Biological Psychiatry, 65, 1099-1102.

Mason O, Morgan CJA, Dhiman SK, Patel A, Parti N, Patel A, Curran HV (2009) Acute cannabis use causes increased psychotomimetic experiences in individuals prone to psychosis. Psychological Medicine, 39, 951-956.

Morgan CJA
, Bedford NJ, O'Regan A, Rossell SL (2009) Is Semantic Processing Impaired in Individuals with High Schizotypy? Journal of Nervous and Mental Disease, 197, 232-238.

Stefanovic A, Brandner B, Klassen E, Cregg R, Nagaratnam M, Bromley L, Das RK, Rossell SL, Morgan CJA, Curran HV (2009) Acute and Chronic Effects of Ketamine on Semantic Priming: Modelling Schizophrenia? Journal of Clinical Psychopharmacology, 29, 124-33.

Blagrove M, Morgan CJA, Curran HV, Bromley L, Brandner B (2009) The incidence of unpleasant dreams after sub-anaesthetic ketamine. Psychopharmacology 203, 109-120.

Morgan CJA, Muetzelfeldt L, Curran HV (2009) Ketamine use, cognition and psychological well-being: a comparison of frequent, infrequent and ex users with polydrug and non-using controls. Addiction 104 (1), 77-87.

Friswell J, Phillips C, Holding J, Morgan CJA, Brandner B, Curran HV (2008). Acute effects of opioids on memory functions of healthy men and women. Psychopharmacology 198(2), 243-250.

Muetzelfeldt L, Kamboj S, Rees H, Taylor J, Morgan CJA & Curran HV (2008). Journey through the K-hole: phenomenological aspects of ketamine use. Drug and Alcohol Dependence 95(3), 219-229.

Morgan CJA & Curran HV (2008) Effects of cannabidiol on schizophrenia-like symptoms in cannabis users. British Journal of Psychiatry. 192: 306-307.

Mason O, Morgan CJ, Stefanovic A, Curran HV (2008). The Psychotomimetic States Inventory (PSI): Measuring psychotic-type experiences from ketamine and cannabis. Schizophrenia Research 103, 138-42.

Morgan CJA, Rees H, Curran HV (2008) Attentional bias to incentive stimuli in heavy ketamine users, Psychological Medicine 38, 1331-40.

Ulhaas PJ, Curran HV, Millard I, Muetzelfeldt L, Morgan CJA (2007) Perceptual organization in ketamine users: preliminary evidence of deficits on night of drug use but not 3 days later. Journal of Psychopharmacology, 21 (3) 347-352.

Morgan CJA & Curran HV (2006) Acute and chronic effects of ketamine upon human memory: a review. Psychopharmacology 188(4): 408-24.

Morgan CJA, Bedford NJ, Rossell SL (2006) Evidence of semantic disorganisation using semantic priming in individuals with high schizotypy, Schizophrenia Research, 84 (2-3): 272-80.

Morgan CJA, Perry EB, Cho HS, Krystal JH, D’Souza DC (2006) Greater vulnerability to the amnestic effects of ketamine in males, Psychopharmacology, 187(4): 405-414.

Morgan CJA, Rossell SL, Pepper F, Smart J, Blackburn J, Brandner B, Curran HV (2006) Semantic priming acutely in healthy volunteers following an acute dose of ketamine and ‘chronically’ in substance users. Biological Psychiatry, 59 (3): 265-72.

Morgan CJA, Mofeez A, Bradner B, Bromley L, Curran HV (2004). Acute effects of ketamine on memory systems and psychotic symptoms in healthy volunteers. Neuropsychopharmacology, 29: 208-218.

Morgan CJA, Mofeez A, Bradner B, Bromley L, Curran HV (2004) Ketamine is positively reinforcing and impairs response inhibition in healthy volunteers – a dose-response study. Psychopharmacology, 172: 298-308.

Morgan CJA, Ricelli M, Maitland CH, Curran HV (2004). Long-term effects of ketamine abuse: evidence for a persisting impairment of source memory in recreational users. Drug and Alcohol Dependence, 75(3):301-8.

Morgan CJA, Monaghan L, Curran HV (2004). Beyond in the K-hole: A 3 year longitudinal investigation of the effects of ketamine on cognition and subjective symptoms, in recreational users who have substantially reduced their use of the drug. Addiction, 99(11):1450-61. 

Pilling S, Bebbington P, Kuipers E, Garety P, Geddes J, Orbach G, Morgan CJA (2002). Psychological treatments in schizophrenia: I Meta-analysis of family interventions and cognitive behavioural therapy. Psychological Medicine, 32: 763-782.

Pilling S, Bebbington P, Kuipers E, Garety P, Geddes J, Martindale B, Orbach, G, Morgan CJA (2002). Psychological treatments in schizophrenia: II Meta-analysis of randomised controlled trials of social skills training and cognitive remediation. Psychological Medicine, 32, 783-791.

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