Professor Willie Motherwell FRS FRSE

Alexander Williamson Professor of Chemistry

Organic Chemistry and Chemical Biology

Professor Willie Motherwell

Address: Department of Chemistry, UCL
Phone No: +44 (0)20 7679 7533
Fax No: +44 (0)20 7679 7524
Extension: 27533
Photo of Willie Motherwell

Research areas of interest include:

  • Organic synthesis
  • Preparative Radical Reactions
  • Metal Catalysed Reactions
  • Organozinc Carbenoids
  • Selective Fluorination
  • Molecular Recognition and Artificial Enzymes 


William B Motherwell Research Image

Research within the Motherwell group addresses a wide variety of fundamental questions from the invention of new and unusual reactions in organometallic and free radical chemistry through to molecular recognition, non covalent interactions and artificial enzymes. 

Research Profile

Selected Publications

  1.  W.B.Motherwell, J. Moise, A.E. Aliev , M. Nic, S.J .Coles, P.N .Horton, M.B. Hursthouse, G. Chessari, C.A. Hunter and J.G. Vinter,Some Studies of Noncovalent Functional Group – Arene Interactions.,Angew Chem. Int. Ed n, 2007 46(41) 7823-7826 DOI:10.1002/anie.200701463.
  2. W.B.Motherwell and A. J.Whitehead , A Convenient One-Pot Aza-Annulation of Primary Amines, Acryloyl Chloride and Electron – Deficient Allenes,. P. J. Gray, Synlett, 2007, 431- 434.  
  3. W. B. Motherwell, G.Bégis, D. E. Cladingboel, L. Jerome and T. D. Sheppard , Observations on the direct amidocyclopropanation of alkenes using organozinc carbenoids, Tetrahedron, 2007 63 6462-6476 
  4. M. Freiria, A.J. Whitehead, D.A. Tocher, W.B. Motherwell, Further observations on the rhodium(I)- catalysed tandem hydrosilylation-intramolecular aldol reaction. Tetrahedron, 2004, 60, 2673-2692
  5. W.B.Motherwell and L. Storey, Some studies on nucleophilic trifluoromethylation using the shelf-stable trifluoromethylacetophenone-N,N-dimethyltrimethylsilylamine adduct. Journal of Fluor. Chem., 2005, 126,491-498. Special Issue dedicated to Professor R. Chambers.

All Publications