Dr Mike Porter
Organic Chemistry and Chemical Biology
Dr Mike Porter
Address: Department of Chemistry, UCL
Phone No: +44 (0)20 7679 4710
Fax No: +44 (0)20 7679 4673
Research areas of interest include:
- Total synthesis
- Metal Carbenes
- Ylide rearrangements
- Biomimetic synthesis
Our research targets the synthesis of complex biologically active molecules which can then be used as probes to target biological function. Current targets have potency as RNA polymerase inhibitors, antibiotics and cytotoxins. We generally need to develop new methodology to carry out our syntheses, and this has led us into a variety of areas including metal carbenes, carbohydrate chemistry and photochemistry.
- A.J.P. Mortimer, P.S. Pang, A.E. Aliev, D.A. Tocher and M.J. Porter. Concise synthesis of bicyclic aminals and their evaluation as precursors to the sarain core. Org. Biomol. Chem. 2008, 6, 2941-2951.
- A.R Ellwood, A.J.P. Mortimer, D.A. Tocher and M.J. Porter. Diastereoselective thia-Claisen rearrangement of pyrrolidinone-derived ketene N,S-acetals. Synlett 2008, 2199-2203. [Correction: Synlett 2009, 3052.]
- A.J.P. Mortimer, A.E. Aliev, D.A. Tocher and M.J. Porter. Synthesis of the tagetitoxin core via photo-Stevens rearrangement. Org. Lett. 2008, 10, 5477-5480.
- A.R. Ellwood and M.J. Porter. Selective conversion of alcohols into alkyl iodides using a thioiminium salt. J. Org. Chem. 2009, 74, 7982-7985.
- J.R.H. Plet, A.K. Sandhu, M. Sehailia and M.J. Porter. Approaches to tagetitoxin and its decarboxy analogue from D-glucose. Synlett 2009, 3258-3262.
- 1988-92 B.A. (Hons.) Merton College Oxford
- 1992-96 D.Phil., University of Oxford, Prof. Jack Baldwin FRS 1996-98 NATO Postdoctoral Fellowship, University of Texas at Austin, Prof. Phil Magnus FRS 1998-99 Postdoctoral research, University of Liverpool, Prof. Stan Roberts
- 1999-present Lecturer, University College London