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Candy Ng's Webpage

Postgraduate Researcher Email: candy.ng@ucl.ac.uk

Address: Department of Biochemical Engineering University College London Torrington Place London WC1E 7JE United Kingdom

Candy Ng received her first degree as a Master of Biochemical Engineering with Bioprocess Management at University College London in 2008. She is now completing an Engineering Doctorate working with both the Department of Biochemical Engineering and the Department of Chemical Engineering at UCL, in collaboration with Novasep Process.

Research project

Title: Optimum design, operation and control of continuous separation of biomolecules

Supervisors: Dr Eva Sorensen, Dr Daniel Bracewell (Biochemical Engineering, UCL) and Dr Eric Valery(Novasep Process)

Biomolecules have a large and continuously growing market in the biopharmaceutical industry. Their complexity causes major bioprocessing issues in satisfying the stringent regulatory requirements. This has led to slow and expensive research and development to ensure process robustness and cost-effectiveness. Chromatography is one of the dominant steps in the downstream processing of biomolecules and contributes significantly to bioprocessing costs.

Recently, interest in chromatography for bioprocessing has shifted towards multicolumn countercurrent chromatography. Its improved chromatographic performances and economic advantages show great promise to handle the increasing upstream titre and market demand of biomolecules. This project aims to facilitate the applications of multicolumn countercurrent chromatography in the separation of biomolecules. This will be achieved by taking advantage of the collaboration between Novasep Process, the Department of Biochemical Engineering, UCL, and the Department of Chemical Engineering, UCL.

Selected publications

Osuna-Sanchez H, Ng C, Sorensen E, Bracewell D, Valery E. High performance affinity chromatography to optimize purification via protein A capture. presented at Preparative and Process Chromatography (PREP) 2010, Philadelphia, 9-12 May 2010.

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