Cells for Sight News Publication
- New research programme into Aniridia to go ahead at Moorfields Eye Hospital
- CFS will give five paper presentations and two posters at ARVO
- Hannah Levis awarded ARVO International Travel Grant
- UCLB patented technology used to develop a potential new treatment for Corneal Surface Disease
- Stefan Schrader successfully defends his PhD thesis
- Cells for Sight to host 5th Limbal Stem Cell Conference at UCL
- Hannah Levis appears in ESCRS Eurotimes
- Prof Julie Daniels invited speaker at the Gordon Conference in California
- Hannah Levis presents at the BCLA Evening Meeting
- New Postdoc joins the group
- Congrats to Marc for running the Paris Marathon!
- Julie Daniels interview on Insight Radio
- Eye disease cash for TAP Biosystems
- TAP, UCL Receive Additional Funding to Take Biomimetic Cornea into Human Safety Study
- New Scientific Data on use of Stem Cells for Ocular Surface Regeneration Presented by Daniels’ Group at Prestigious Ophthalmology Conference, ARVO
- ARVO 2012 report
- International Conference on Stem Cells and Regenerative Medicine
- Julie Daniels Fellow of the Society of Biology
- Welcome to Nuria Genicio!
- London 2012 Olympics is here!
- Farewell Marina!
- Welcome Sara Galindo!
- New research technician joins CFS
- 5th Limbal Stem Cell Meeting
- Recent Publications from CFS
- Alvena visits Prof. Funderburgh's lab in Pittsburgh
- Sarah and Alvena present at London Matrix Group
- Levis et al. manuscript accepted for publication in PLOS ONE
- Amanda Vernon successfully upgrades from MPhil to PhD
- We welcome a new member of CfS- Louise Morgan
- CfS do Movember!
- CfS Christmas Lunch
- New Endothelial RAFT article published in PLOS ONE available online now
- Aniridia Europe Meeting, Italy 2012
- CfS awarded UCL Beacon Bursary to host public engagement event
- Marc Dziasko successfully upgrades from MPhil to PhD
- Hannah and Victoria attend Aniridia Network UK Conference
- Alvena and Isobel visit Istanbul to attend TERMIS
- Marc attends the ISSCR annual conference
- Julie, Louise, Alex and Steve visit Japan
- Hannah and Marc present at the Vision of Excellence Congress in Berlin
- Cells for Sight team attend the 6th Limbal Stem Cell Forum in Liverpool
- Hannah has her paper published in Biomaterials
- Alex has his paper published in Stem Cells Translational Medicine
- Cornea Connect 2014
- Marc Dziasko has his paper published in PLoS ONE
- Hannah and Victoria raise £115 for Aniridia Network UK
- Cells for Sight team prepare for ARVO
- Julie receives PhD studentship funding from Fight for Sight
- Isobel's paper published in Experimental Eye Research
New research programme into Aniridia to go ahead at Moorfields Eye Hospital
25 April 2012
New research that could offer hope to young people and adults suffering from a type of corneal blindness is to get underway at Moorfields Eye Hospital and the UCL Institute of Ophthalmology, thanks to an outstanding fundraising campaign by a determined Northumberland-based family.
Aniridia is an eye disease that affects one in 100,000 people. It can lead to blindness by affecting several parts of the eye. The new research programme, led by Professor Julie Daniels, under the umbrella of her ‘Cells for Sight transplantation and research programme’, will investigate how cell-to-cell communication is disrupted in the cornea during the progression of aniridia-related keratopathy. The team’s ultimate aim is to develop a cell therapy solution to help patients retain their sight for longer.
Over £65,000 has been raised by Mrs Elly Chapple and her family for the Moorfields Eye Charity‘Shine the light on Aniridia’ campaign. The Chapple’s daughter Ella, has aniridia and glaucoma in her right eye. The funds they raised have been matched by the ‘Cells for Sight’ programme to enable the research to get underway. The first important milestone as a result of the fundraising initiative has been the appointment of ophthalmic scientist Dr Victoria Tovell, who will work to develop a human model of the aniridia-related keratopathy disease.
To date, Moorfields and the Cells for Sight team, have had some success in using stem cell therapy to treat some adults with advanced aniridia. Building on the results of that work - and early data from previous stem cell research - the team decided to focus on the role of defective communication between stem cells and their supporting cells in the cornea.
Professor Julie Daniels said: “By focusing on this aspect of the disease we can begin to answer why cell communication breaks down. This is an important first step in learning how the disease progresses. The research programme is very challenging but if it succeeds it will literally ‘shine a light’ on the understanding we need to develop therapies to prevent progression of aniridia-induced corneal blindness in younger people.
“We are delighted to be at the forefront of this exciting new programme of research. We could not undertake this without the money raised by the Chapple family. It is a huge boost to our work which has the potential in future years to make a difference to the lives of children like Ella Chapple whose sight will need saving.”
Donations to the Moorfields Eye Charity ‘Shine the Light on Anirida’Campaign are on going and more details on how to donate are available on 020 7566 2565 or by email to firstname.lastname@example.org
For more information about Aniridia:
Published 19 December 2011 on Moorfields Eye Hospital NHS webpage
Page last modified on 25 apr 12 13:32