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CDB Seminars
All welcome

Thursday April 24th, 1pm
Prof Justin Blau, NYU
Title: How flies time: Neurobiology of the Drosophila circadian clock
Host: Prof Ralf Stanewsky
Venue: Anatomy G04 Gavin de Beer LT

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Friday April 25th, 1pm
Dr Benedetta Ruzzenente, Max Planck Institute
Title: RNA Metabolism in Mitochondria: Lessons from the Mouse
Host: Prof Michael Duchen
Venue: Medawar G02 Watson LT

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Thursday May 1st, 1pm
Dr Setsuko Sahara, MRC - Kings
Title: Control of cortical neuron number
Host: Prof John Parnevelas
Venue: Anatomy G04 Gavin de Beer LT

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Thursday May 8th, 1pm
Prof Robert Lightowlers, Newcastle University
Title: Mitochondrial gene expression in humans: a tale of two tales
Host: Dr Gyorgy Szabadkai
Venue: Medical Sciences 131 A V Hill LT

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Dr Gyorgy Szabadkai

Dr Szabadkai

Senior Lecturer


g.szabadkai (at) ucl.ac.uk

Telephone:
Office: 020 7679 7362
(Int: 37362)

Research

I'm currently on leave, working at the University of Padua (UoP) and establishing the UCL-UoP collaborative Mitochondrial Research Platform.

The interest of my research groups is to understand the role of mitochondria in cellular stress responses in major pathologies such as neurodegenerative disease and cancer. We use bioinformatics, biochemical, molecular biology and cellular imaging tools in collaboration with other mitochondrial biology and imaging groups at the UCL and UoP.

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Schematic outline of our research Stress conditions, accompanying several pathologies like neurodegenerative diseases, diabetes and cancer induce adaptive responses in both the mitochondrial and ER networks. This includes an increased turnover of organelle biogenesis and degradation (autophagy). If adaptation fails, cells utilize different pathways to die.  ER-mitochondrial crosstalk and transcriptional regulation of the mitochondrial proteome (biogenesis) determine both adaptive and death responses and thus will be a target of cellular stress signaling pathways.

Lab members at UCL:

Robert Bentham (UCL COMPLeX, British Heart Foundation PhD fellow)

Julia Hill (Eisai funded PhD fellow)

Gregory Keen (Research Assistant, UCL-Eisai Therapeutic Innovation Group)

Thomas Briston (Research Assistant, UCL-Eisai Therapeutic Innovation Group)

Ronan Astin (Clinical PhD fellow)

Page last modified on 23 feb 14 17:41 by Gyorgy Szabadkai