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CDB Seminars
All welcome

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All Seminars are held in the Gavin De Beer Lecture Theatre, Anatomy Building, Thursday 1-2pm

18 Sept: Katarzyna Anton (Tada lab) / Mae Woods (Barnes lab)

2 Oct: Helena (Wilson lab) /Maria Maiaru (Geranton lab)

16 Oct: Tom Wyatt (Charras lab) (Oates lab)

30 Oct: Harold Burgess - Title TBC (Host: Prof Steve Wilson)

31 Oct: SPECIAL SEMINAR - Sophie Jarriault (IGBMC) – Title TBC (Host: Dr Richard Poole)

6 Nov: Aude Marzo (Salinas lab)/ Maite Ogueta (Stanewsky lab)

13 Nov: (Paluch lab)/ Robert Bentham (Szabadkai lab)

27 Nov: Irene (Stern lab)/Cristina Benito(Jessen lab)

11 Dec: Marcus Ghosh (Rihel lab)/ (Chubbs lab)

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Wellcome PhD Students: Final Year Talks

Thursday 25 September

12.30-2.35pm

Room 249, 2nd Floor, Medical Sciences Building, Gower Street

12.30pm:  Scott Curran

12.55pm:  Kristina Tubby

1.20pm:  Miguel Tillo

1.45pm:  Alex Sinclair-Wilson

2.10pm:  Elena Scarpa

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Prof Sandip Patel

Prof Sandip Patel

Professor of Cell Signalling

patel.s@ucl.ac.uk

Telephone:
Office: 020 7679 4437
(Int: 34437)

Research

Intracellular Calcium Mobilising Messengers
Increases in cytosolic calcium levels are pivotal for the regulation of a wide range of cellular processes. Paradoxically, calcium can activate opposing cellular fates and understanding how calcium exerts such exquisite specificity is a subject of intense study. Different extracellular stimuli may utilise distinct combinations of intracellular calcium mobilising messengers to generate specific calcium “signatures”. These temporally and spatially complex calcium signals can then be decoded by the cell to achieve a given cellular response.

Areas of interest


Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) - A Novel Intracellular Calcium Mobilising Messenger
We are investigating the role of the newly described calcium mobilising agent, nicotinic acid adenine dinucleotide phosphate (NAADP), in the control of calcium dynamics in several systems including sea urchin eggs, pancreatic acinar cells and neurons. Projects are aimed at characterising the spatial aspects of NAADP-induced calcium increases using digital imaging techniques, measuring cellular NAADP levels in response to physiological stimulation, defining the enzymatic route for NAADP synthesis and metabolism and identifying the putative NAADP receptor and enzymatic machinery at the molecular level.

Publications

View all of Prof Patel's publications via the UCL Research Publications System

Page last modified on 07 jun 13 10:12 by Edward D Whitfield