UCL Institute of Cardiovascular Science
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Structural heart disease
Structural heart disease can be described as a structural or functional abnormality of the heart (or blood vessels supplying the heart), which impairs normal functioning. This may include congenital heart defects such as coarctation of the aorta and atrial septal defects; or structural heart disease acquired due to aging, injury or infection such as valvular disease.
Interventional repair for structural heart defects has been growing with new and varied approaches to percutaneous treatment as well as expanded indications for treatment. Device-based therapeutic approaches now play an increasing role in treatment particularly in patients with cardiovascular abnormalities that are largely hemodynamic and mechanical in nature. Our work at the Institute of Cardiovascular Science ranges from Mathematical Modelling of this disease and potential interventions, to delivery of cutting edge treatments for patients.