Open Biosystems pGIPZ shRNAmir library
We have the Human and Mouse Open Biosystems GIPZ shRNAmir lentiviral libraries. Both libraries contain over 100,000 active clones, each containing a unique hairpin to target knockdown of genes within the Human and Mouse genomes respectively.
The design of the hairpins contained within the GIPZ vector is based on the endogenous mir-30. By mimicking an endogenous RNA, the GIPZ hairpin is efficiently processed in vivo allowing for a more effective knockdown of your gene of interest.
GIPZ vector design
The GIPZ lenti-vector contains various features to allow effective expression, tracking and versatility of your hairpins.
These features include:
- CMV (Pol II) promotor
- Turbo GFP to mark shRNAmir expression
- Puromycin selectable marker
- Lentiviral vector to allow successful transduction of primary, non-dividing and other difficult to transduce cells.