UCL Cancer Institute

Open Biosystems pGIPZ shRNAmir library



We have the Human and Mouse Open Biosystems GIPZ shRNAmir lentiviral libraries. Both libraries contain over 100,000 active clones, each containing a unique hairpin to target knockdown of genes within the Human and Mouse genomes respectively.


shRNAmir


The design of the hairpins contained within the GIPZ vector is based on the endogenous mir-30. By mimicking an endogenous RNA, the GIPZ hairpin is efficiently processed in vivo allowing for a more effective knockdown of your gene of interest.


GIPZ vector design


The GIPZ lenti-vector contains various features to allow effective expression, tracking and versatility of your hairpins.

These features include:

  • CMV (Pol II) promotor
  • Turbo GFP to mark shRNAmir expression
  • Puromycin selectable marker
  • Lentiviral vector to allow successful transduction of primary, non-dividing and other difficult to transduce cells.



Links


 

Contacts


Catherine King
0207-679-6506
catherine.king@ucl.ac.uk

 



 

Links


Please refer to the GE website for further information about our libraries.