Enquiries to:
Kerry Wynn-Williams
Tel: 020 76796549 (or x 46549)
E-mail:
k.wynn-williams@ucl.ac.uk
The UCL Cancer Institute hosts external speakers, prominent in their fields of study, on Thursday evenings throughout the academic year.
The aims of these seminars are to discuss a range of topics relevant to cancer research, from fundamental research discoveries to translational applications, and we hope that these seminars will become a focus of social interaction between clinicians and scientists involved in cancer research across the UCL campus.
The general format is a 40-minute talk followed by a 10-minute discussion. A drinks reception will be held after each seminar.
Thursday 20th June at 5pm in the Courtyard Café, Paul O’Gorman Building
Dr Simon Cook –
The Babraham Institute, Cambridge
“Acquired resistance to targeted protein kinase inhibitors: causes, consequences & some solutions“
Dr Simon Cook has a long standing interest in signal transduction cascades. The aim of his laboratory is to understand how selected pathways function in stress responses and stress resistance and how this impacts on cellular lifespan. In particular, his laboratory is interested in pathways that play central roles in coordinating cell division, cell survival and cell adaption (collectively cell longevity) in response to growth factors, stresses and nutritional cues. Therefore, his laboratory currently focuses on four evolutionary conserved signalling systems, namely the mTOR, MAPK, DYRK and NAD+ salvage pathways. Besides these basic research efforts, the Cook laboratory is also studying how human tumour cell lines with defined oncogenic driver mutations (e.g. mutations in KRAS or BRAF) adapt to inhibitors of the MAPK (ERK1/2) pathway. Studies of novel FGFR inhibitors are also ongoing in his laboratory. Dr Cook will present their recent progress in understanding these essential signalling networks on the basic biology level in addition to presenting outcomes of ongoing translational research projects.
For further info homepage: Dr. Simon Cook
See also: http://www.babraham.ac.uk/pjl_pages/cook/research.html and http://www.babraham.ac.uk/pjl_pages/cook/kec.html
Host: Alexander Hergovich – please contact Dr Alexander Hergovich if you wish to meet with the speaker.
All are welcome. A reception will be held after the seminar.
Past Seminars
Autumn2012 (pdf)
Speakers - Prof Laurence Pearl, Prof Stephen Russell, Dr Helfrid Hochegger, Prof Kate Vallis, Dr Ricky Sharma, Prof Gerard Evan, Prof Bryan Cullen, Prof Genevieve Almouzni, Dr Rob Klose, Prof Victor Tybulewicz
Spring2012 (pdf)
Speakers - Dr Eric O’Neill, Professor Johann de Bono, Professor Johann de Bono, Dr Mikhail Spivakov, Dr Simon Cook, Professor Alan Ashworth, Professor Wendy Bickmore, Professor Paul Clarke, Dr Gordon Peters, Professor Neil Brockdorff, Dr Gareth Inman
Autumn2011 (pdf)
Speakers - Professor Timothy Bestor, Dr Paresh Vyas, Professor Eric So, Dr Kim Jensen, Dr Eyal Gottlieb, Professor Sarah Bray, Dr Nitzan Rosenfeld, Professor Pascal Meier, Dr Martin Zeidler, Professor Chris Marshall, Dr Andrew Bushell, Dr John Stingl, Professor Jordan Raff, Professor Hans Lehrach, Dr Ana Pombo
Spring2011 (pdf)
Speakers - Anne Ferguson-Smith, Professor Nick Proudfoot, Dr M Madan Babu, Professor Dave Tuveson, Professor Henk Stunnenberg
Spring2010 (pdf)
Speakers - Taija Makinen, Tony Kouzarides, Salvador Moncada, Mark Emberton and Mr Hashim Ahmed, Hing Leung, Nic Tapon, Margaret Ashcroft, Karim Malik, Gail Risbridger, Erik Sahai, Michael Streckel
Micro RNAs and Cancer Seminar 2010 (pdf)
Speakers - Reuven Agami, Adam Baker, Carlos Caldas, Doug Hanahan, Paul Kellam, Dimitris Lagos, Andres Ramos, Stephanie Urschel, Andrea Ventura, Elena Vigorito, Yosef Yarden, Carlo Croce
Winter 2009 (pdf)
Speakers - Nicholas Wright, Richard Peto, Hilary Calvert, Peter Ell, Jack Cuzick, Andy Futreal, Caroline Hill, Peter Parker, Stephen Jackson, Ewan Birney
Spring 2009 (pdf)
Speakers - Simon Gayther, Sue Hadjur, Marianne Bronner-Fraser, Fiona Watt, Ruth Muschel, Anne Ridley, Steve Pollard, Rebecca Fitzgerald, Antonis Kirmizes, Michael Baum, Andy Futreal, Megan Cully
Winter 2008 (pdf)
Speakers - Tony Ng, Julie Cooper, Amanda Fisher, Barbara Jennings, Mark Lythgoe, Robert Brown, Julian Blow, Caroline Dive, James Brenton, Francesco Dazzi, Quentin Pankhurst
Summer 2008 (pdf)
Speakers - Julian Downward, Ian Hagan, Mieke Dewerchin, Jordan Raff, Silvia Marino, Gordon Jayson, Kim Nasmyth, Tony Carr
Winter 2007 (pdf)
Speakers - Hans Stauss, Chris Marshall, Ronjon Chakraverty, Bryan Young, Alison Lloyd, Charles Swanton, Buzz Baum, Andrew Tutt, Gareth Williams, Tariq Enver, Jane Wardle, Mike Stratton, Bart Vanhaesebroeck
Summer 2007 (pdf)
Speakers - Tim Hunt, Chris Boshoff, Kevin Harrington, Stephan Beck, John Anderson, Tim Crook, Adrian Harris, Xin Lu, Martin Widschwendter, Robin Weiss, Ron Laskey, Frank Uhlmann, Bruce Ponder
