UCL Cancer Institute

iPSC Methylome


iPSC Methylome

Project Leader: Lee Butcher



Induced pluripotent stem cells (iPSC) are pluripotent cells derived from reprogramming of non-pluripotent cells such as fibroblast or blood cells. iPSC have great potential for regenerative and therapeutic medicine. The aim of this project is to assess the efficiency of different reprogramming protocols using whole-genome DNA methylation (methylome) analysis.







iPSC Methylome


The UCL Cancer Institute, University of Cambridge, CellCentric, Sigma-Aldrich and TAP embark on a collaboration (CellCentric Press Release) to define markers of epigenetic reprogramming, supported by £1.1m from the UK Governmentís Technology Strategy Board.



Project Members


Tiffany Morris
Lee Butcher
Stephan Beck



Collaborators


Anne Ferguson Smith
Ludovic Vallier
CellCentric
The Automation Partnership
Sigma-Aldrich





 

Project Leader

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Lee Butcher, PhD
Medical Genomics
UCL Cancer Institute
University College London
Paul OíGorman Building
72 Huntley Street
London WC1E 6BT, UK
Tel: +44-20-7679-6004
l.butcher@ucl.ac.uk