UCL Cancer Institute

Head and Neck Cancer Epigenome Project

Head neck

Project Leader: Matthias Lechner

Head and Neck Squamous Cell Cancer (HNSCC) is the sixth most common cancer worldwide and increasingly caused by infection with human papilloma virus (HPV). The aim of this project is to analyse HPV and non HPV-associated HNSCC epigenomes for differences in DNA methylation and microRNA expression. This work is expected to increase our understanding of virus-induced HNSCC carcinogenesis and potentially lead to novel molecular markers for risk prediction, early diagnosis and therapeutic targets.

Head and Neck Cancer Epigenome Project

Project Members

Matthias Lechner
Andy Feber
Lee Butcher
Gareth Wilson
Stephan Beck


Chris Boshoff


Project Leader

Matthias Lechner, MD, MRCS
Medical Genomics
UCL Cancer Institute
University College London
Paul O’Gorman Building
72 Huntley Street
London WC1E 6BT, UK
Tel: +44-20-7679-6004