UCL Cancer Institute

Head and Neck Cancer Epigenome Project


Head neck

Project Leader: Matthias Lechner



Head and Neck Squamous Cell Cancer (HNSCC) is the sixth most common cancer worldwide and increasingly caused by infection with human papilloma virus (HPV). The aim of this project is to analyse HPV and non HPV-associated HNSCC epigenomes for differences in DNA methylation and microRNA expression. This work is expected to increase our understanding of virus-induced HNSCC carcinogenesis and potentially lead to novel molecular markers for risk prediction, early diagnosis and therapeutic targets.







Head and Neck Cancer Epigenome Project


Project Members


Matthias Lechner
Andy Feber
Lee Butcher
Gareth Wilson
Stephan Beck



Collaborators


Chris Boshoff





 

Project Leader

Matthias Lechner, MD, MRCS
Medical Genomics
UCL Cancer Institute
University College London
Paul O’Gorman Building
72 Huntley Street
London WC1E 6BT, UK
Tel: +44-20-7679-6004
m.lechner@ucl.ac.uk