Image of the Month

Image of the Month

Cardiovascular MRI

Cardiac Imaging

Cardiac imaging is technically challenging as the heart is literally a moving target. Beating 10 times faster than the human heart, we can now capture a mouse heart beat in a fraction of a second using our state-of-the-art MRI system funded by the British Heart Foundation. These ultrafast techniques are used to generate information about cardiac structure, function, tissue health and cellular viability. In collaboration with Mark Pepys, Paul Riley, Derek Hausenloy, we are using our high-speed imaging techniques and novel forms of image contrast to study life-threatening diseases such as amyloidosis and heart attacks. Our aim is to use a cross-disciplinary approach to tackle heart disease, which remains the leading cause of death in the developed world.

Stem cell therapies for myocardial infarction


Incidence of cardiovascular diseases has continued to rise despite better  understanding in their pathogenesis, and while mortality is declining with advances in treatment, morbidity has increased dramatically due to chronic complications from surviving the initial event. In contrast to existing interventions which primarily aim at limiting tissue damage, stem cell therapy has recently emerged as a novel interventional paradigm where damaged myocardial and other vascular tissues can be regenerated and repaired through transplantation of these primitive cells. This project involves a number of studies that aim to investigate some of the therapeutic effect of stem cells in cardiovascular diseases; in particular, we aimed to elucidate the potential cardioprotection offered by stem cells in the very early phase following myocardial ischaemia-reperfusion injury by using cardiac magnetic resonance imaging.


Video by Adrienne Campell

Page last modified on 12 sep 11 13:44