CABI

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In Vivo Irradiation

CT-guided in vivo irradiation

InVivoIrradiation

Radiation remains a critical component of cancer treatment and advances in radiotherapy technology have transformed the applications of this modality in the clinic.  There is a pressing need for pre-clinical irradiation studies to reflect these developments.

State of the art pre-clinical irradiation will be available from 2011 using Xstrahl's (previously known as Gulmay) Small Animal Radiation Research Platform (SARRP).  This system allows accurate, reproducible targeted irradiation of tumour or normal tissue targets in small animals using CT-guided localization. This will transform the utility of pre-clinical models in radiation research since it can mimic clinically delivered fractionated radiotherapy or radiosurgery. UCL researchers and collaborators will be able to use this platform to test tumour and normal tissue radiobiology in a unique way or as an alternative to invasive methods to produce well defined lesions in organs such as brain with sub-millimeter targeting accuracy.

The combination of highly accurate radiation delivery using SARRP with pre-clinical imaging modalities available at CABI will represent a unique environment for pre-clinical research.

Contact Dr Susan Short for more information.

Page last modified on 14 oct 11 14:15