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Study that began in 1980s enables researchers to develop understanding of phenotypic heterogeneity in familial Alzheimer’s
Published: Oct 28, 2016 1:37:50 PM
Biomedical Research Unit
The Queen Square Dementia BRU focuses on young onset dementias in order to achieve our aims of developing new methods of diagnosis and treatment.
Young onset Alzheimer’s disease and other degenerative dementias often occur on an inherited (autosomal dominant) basis with the same clinical features as non-inherited (sporadic) disease. Identification of the mutated genes causing the dementia and longitudinal study of individuals who carry the gene create a window on the disease process.
In 2012 the National Institute for Health Research (NIHR) created four Dementia Biomedical
Research Units, that have been working in close collaboration to support experimental medicine in dementia and to help
meet the Prime Minister's Dementia Challenge.
Dementia poses one of the greatest challenges facing society - the loss of the mental faculties that define us as humans is a personal and family tragedy. At a society level it presents a potential financial disaster as we face an increasingly aged population.
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