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Biochemical Engineering

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Computer Aided Bioprocess Engineering

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Course Title BENG3009
Level Three
Credits 0.5
Course Tutor Dr Yuhong Zhou
Assessment Two-hour written examination (65%)
Three pieces of coursework (35%)
Prerequisites BENG206P and second year courses related to process engineering and unit operations. 

Aims

This course is designed to help students to develop knowledge of how to use IT software, acquire elementary programming skills and numerical methods to solve bioprocess problems; to be aware of the concepts of bioprocess dynamics and control for product quality and plant safety.

Learning Hours

Includes:

Lectures: 35h
Computer programming workshops: 30h
Case studies: 60h

Syllabus

Whole bioprocess modelling and simulation

Introduction to Bioprocess Design
Introduction to BioSolve
Process configuration
Mass balance, equipment sizing and Cost analysis
Whole bioprocess analysis
Whole bioprocess debottleneck

Advanced Bioprocess kinetic modelling, Simulation and Design

Homogenisation modelling and simulation II
Centrifugation modelling and simulation II
Process integration
Determine "Window of operation"

Bioprocess Control

Bioprocess dynamic modeling
Laplace transform and transfer function
Prediction of process dynamic behaviours
Controller design
PID tuning method