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Biochemical Engineering

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Fluid Flow and Mixing in Bioprocesses

We are in the process of updating our website and will upload new and more comprehensive module descriptions in the coming weeks.

Course Code
BENG103P
Level One
Credits
0.5
Course Tutor
Dr Marco Marques
Assessment Criteria
Coursework: 20%
Unseen Examination: 80%
Prerequisites
None

Aims

To provide you with an introduction to the basic transport phenomena required to analyse and design processes handling labile biological materials.

Learning Hours

Includes:

Seminars/problem classes/tutorials: 32h
Laboratory/studio: 18h
Independent project work: 10h
E-learning/tutor led contact: 30h
E-learning/student led contact: 10h

Syllabus

  • Rheology: Viscosity and shear stress. Newtonian and non-Newtonian fluids. Rheology of fermentation broths.
  • Fluid flow in pipes: Predicting flow characteristics in pipe systems. Calculating head in a pipework system. Case study. Pumping of Liquids. Fluid flow and pressure measurement.
  • Fluid flow in packed columns: Flow through porous media. Determining column porosity. Estimating pressure drops in packed beds. Effect of particle shape. Case studies- Pumping and flow in chromatography columns.
  • Bioreactor mixing and scale-up/down: Flow patterns in stirred tanks. Quantification of mixing phenomena in stirred vessels. Case Study 1 – Design of batch sterilisation vessel and small aerated pilot fermenter. Influence of power input on oxygen transfer. Case Study 2 -  Scale-up/down of fermenters.