Biochemical Engineering


Mrs Ludmila Ruban

Cell Therapy Research Facilitator and Training Coordinator

Research Interests


Ludmila has over 20 years experience in cell biology and more than 12 years experience in stem cell biology. She began work on human embryonic stem cells (hES) in the Centre for Stem Cell Biology at Sheffield University. The Centre was awarded one of the first two licences granted by the UK HFEA for derivation of hES cells.  Ludmila was one of the first in the country to start working with the Wisconsin hES lines. She was instrumental in the derivation of seven new human embryonic stem cell lines.

Ludmila has been actively involved in training of national and international researchers within the Centre. She also coordinated, organised and taught at the annual practical training course for academics: ‘Working with Human Embryonic Stem Cells’. Ludmila has established a collaboration with UK Stem Cell Bank, ongoing since 2003. Inputs include being an advisor to their technical forum – an annual program and workshop on hES cells. In 2006 Ludmila joined UCL and the Department of Biochemical Engineering.


Ludmila’s research remains primarily in the area of human embryonic stem cells, specifically the optimization of tissue culture conditions for stem cell lines and the optimization of the robust processes for the cell therapy manufacturing. She also has an interest in stem cells Bioprocessing.

Ludmila Ruban is the author of a new book on the subject entitled: ‘Human pluripotent stem cells in culture’, recently published by Springer.

Mrs Ludmila Ruban

Mrs Ludmila Ruban



  • Cell Therapy Research Facilitator and Training Coordinator
    Dept of Biochemical Engineering
    Faculty of Engineering Science

Joined UCL


Teaching and Training Activities

  • Designed, organized and ran the newly established annual International practical course ‘Human embryonic stem cells in culture’. The course is designed for life science and engineering graduates new to stem cell culture or for more experienced individuals new to working with iPSC or hES cell lines.
  • Design and run practical course for the first year postgraduates: ‘Emerging Technologies’, BENG GP27, including lecturing on: ‘Human embryonic stem cells in culture’.
  • Adviser for the postgraduate and undergraduate course: ‘Pilot Plant Processing ‘BENG G012.
  • Co-supervisor for several engineering doctoral projects with the London Regenerative Medicine Initiative focused on using process engineering approaches to improve stem cell bioprocessing funded by UK Stem Cell Foundation and EPSRC
  • Oversees the tissue culture training of all postgraduates in the department and training in tissue culture of embryonic stem cell lines in the Regenerative Medicine Bioprocessing Units
  • Runs an introductory workshop on basic tissue culture for Postgraduates during Induction Week