UCL DEPARTMENT OF BIOCHEMICAL ENGINEERING

Biochemical Engineering

• Home
• About
• Degrees
• Research
  • MBI® Training
    • MBI® courses
    • MBI® e-learning
      • e-module booking
    • News
    • MBI® gallery
  • BiCE
  • IMRC
  • RegenMed
  • EngD collaborations
  • Work with us
  • Bioprocessing Matters
  • VISION executive training
  • EPSRC Centre
  • Industry
• Alumni
• Intranet
• Contact

Successful Bioreactor Mixing

This course focuses on how to define conditions for the successful scale-up or scale-down of a fermentation process. It considers how to calculate the power input required for agitation in a stirred-tank fermenter under a range of operating conditions, and the impact of mixing and power input on oxygen transfer in aerobic fermentations and on different types of cells.

Course Overview

• Introduction
• Quantification of Mixing Phenomena in Stirred Vessels
• What you will Learn
• Case Study Outline
• Effect of Aeration on Power Input
• The Influence of Power Input on Oxygen Transfer
• The Influence of Agitation on Cells
• Fermenter Scale-Down
• Rules of Thumb for Scaling
• Other Relevant Stirred Vessels
• Appraisal

What you will learn

The learning outcomes of this course are:

• To be able to calculate the power input required for agitation in a stirred-tank fermenter under a range of operating conditions
• To be able to define conditions for the successful scale-up or scale-down of a fermentation process
• To have an understanding of the impact of mixing and power input on oxygen transfer in aerobic fermentations and on different types of cells
• To have an understanding of how the operation of the fermenter can impact on the initial stages of product recovery

Sample pages

• 
• 
• 

---