Current Challenges in Mammalian Cell Processing

Industrial platforms, Underpinning bioscience, Novel technologies

27-29 January 2014

Mammalian cells have become the workhorse of the biotech industry due to their ability to produce of functional complex macromolecules at scale. The Mammalian Cell Processing MBI module is a three day course focusing on the specific challenges and opportunities associated with these cells.  The course gives delegates a unique insight into platform technologies developed by world leaders in the field such as Lonza Biologics, MedImmune and Life Technologies.  Talks from internationally renowned academics will discuss the underpinning bioscience and novel technologies  currently in development to meet future demand.

There will also be the opportunity to interact with UCL’s extensive macromolecular research program (www.epsrc-cim-macromoleculartherapies.ac.uk) with particular focus on our new and unique single-use facility.   Talks, tours and networking opportunities are supplemented with an interactive industryled case study which puts delegates in a real-life process development scenario.

Who should attend?

The course is particularly useful given the highly interdisciplinary  nature of the field. Busy delegates from a wide variety of backgrounds will be given the opportunity to step  back and understand the history behind the current state of the art: robust, efficient and defined production processes. Molecular biologists, process engineers, cell biologists, analytical scientists, project managers and chief scientific  officers are just a few of the professionals that will benefit from the opportunity to shed light on many of the specialised approaches which have become embedded within the industry.

Programme

Day 1

• Historic overview of the field
• Cell line development
• Process development
• Fundamentals of largescale production

Day 2

• Case study: from development to production
• Developing highly productive production processes
• Medium and feeding strategies
• Scale down approach for bioprocess development
• Singe-use processing technologies

Day 3

• Tour of single use facility
• What can fundamental cell biology contribute to mammalian cell bioprocessing?
• The impact of upstream processing on downstream processing
• Quality by design
• Process economics

Teaching Staff

Dr Farlan Veraitch, UCL - Module Leader
Prof John Birch, Independent Consultant
Dr Bo Kara, Fujifilm Diosynth Biotechnologies

Invited Expert Speakers

Jon Dempsey, Life Technologies
Suzanne Gibson, MedImmune
Suzanne Aldington, Lonza Biologics
Michelle Hutton, Lonza Biologics
Colin Jaques, Lonza Biologics
Sakis Mantalaris, Imperial College London
Carol Marshall, GlaxoSmithKline
Mark Smales, University of Kent
Graham McCrest, Fujifilm (TBC)
Martin Smith, Lonza Biologics (TBC)
Martina Micheletti, UCL
TAP Biosystems (TBC)

The module costs £1450, with a £100 discount if you register and pay before 16 December 2013.

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Page last modified on 16 dec 13 09:45