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Male biochemical engineer in lab

We have two vacancies at present:

Post-Doctoral Research Associate - Protein Purification and Process Development: Ref:1584578 

Grade 7
Hours Full Time
Salary
(inclusive of London allowance)
£34,056 - £41,163 per annum

Duties and Responsibilities

The Department of Biochemical Engineering is looking for a post-doctoral research associate to contribute to a project funded by the Bill and Melinda Gates Foundation. The post holder will contribute to the design of a range of experiments in relation to the project, and will require a background in bioseparation in order to carryout preparative chromatography using AKTA equipment and an array of supporting bioanalytical methods. You will also be required to run experiments in consultation with the Principal Investigators, ensuring that experiments are appropriately supervised and supported. To record, analyse and write up the results of experiments. 

The project, as with all of the Gates Foundations projects, is milestone oriented, and this position is for a minimum of two years initially. If milestones are met at the end of two years, the project will be extended by another three years for a total duration of 5-years.

Key Requirements

A PhD or post-doc in a relevant subject area and in particular bioseparations and bioanalytical methods related to vaccine manufacture. The successful candidate should also have knowledge of quantative nucleic acid assays and protein purification, protein analytical skills and protein purification experience from Pichia pastoris and E. coli.

If you have any queries regarding the application process, please contact Dr Tarit Mukhopadhyay t.mukhopadhyay@ucl.ac.uk

  • Closing Date: 8 Oct 2016
  • Latest time for the submission of applications: 23:59

Our department holds an Athena SWAN Silver award, in recognition of our commitment and success in addressing gender equality.

This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. 

Please visit the UCL HR Page for more information on this position Ref:1584578 


BBSRC - Post-doctoral Research Associate in Synthetic Biology and Bioprocess Modelling and Control [two posts available]: Ref:1584538 

Grade 7
Hours Full Time
Salary
(inclusive of London allowance)
£34,056 - £41,163 per annum

Duties and Responsibilities

These two posts are funded as part of a prestigious, 5-year, £3.5M project (ConBioChem), which is supported by the BBSRC Industrial Biotechnology Catalyst Fund. The project involves collaboration with the Universities of Nottingham and Cambridge, and our industrial partners, Lucite International, Ingenza, Green Biologics, CHAIN Biotech and CPI. The aim is to develop continuous bio-manufacturing of platform chemicals, using metabolically engineered microorganisms. Overall, the project seeks to solve a series of key problems relating to continuous bio-manufacturing: (1) genetic instability of metabolically engineered microorganisms; (2) low product concentrations; and (3) speed of translation from the lab to industrial chemicals manufacturing at scale. Research will be undertaken in a large collaborative team comprising 6 postdocs, 6 academics and a project manager at the three universities.

Key Requirements

Synthetic Biology Post 

This 5 year Research Associate position will address the design and engineering of bacterial chasses for the stable, long-term production of commodity chemicals. Specifically the work will address the construction of genetically stable and high producing biocatalyst strains using a variety of synthetic biology methods. The post will also generate data and test data from the other posts in the project including the bioprocess modelling and control post below. 

Candidates will be required to hold a PhD in a relevant discipline (e.g. Biochemistry, Molecular Biology, Biotechnology) and ideally possess experience in one or more of the following areas: recombinant strain construction, pathway engineering, genome integration in bacteria, enzyme expression, use of recombinant bacterial strain stabilizing systems, genetic circuits to ensure stable carriage of production genes. The post holder will report to Prof. John Ward. 

Bioprocess Modelling and Control Post 

This 5 year Research Associate position will address the overall design and implementation of continuous biomanufacturing processes at laboratory and pilot scale. Specifically the work will address the modelling of whole bioprocess sequences and their practical implementation with on-line control systems e.g. NIR spectroscopy. Candidates will be required to hold a PhD in a relevant discipline (Biochemical or Chemical Engineering) and ideally possess experience in one or more of the following areas: bioprocess modelling, bioprocess control, fermentation, on-line bioprocess monitoring. The post holder will report to Prof. Gary Lye. 

Further Details

For informal enquiries please contact Prof John Ward (j.ward@ucl.ac.uk) or Prof Gary Lye (g.lye@ucl.ac.uk).

  • Closing Date: 23 Oct 2016
  • Latest time for the submission of applications: 23:59

Our department holds an Athena SWAN Silver award, in recognition of our commitment and success in addressing gender equality.

This appointment is subject to UCL Terms and Conditions of Service for Research and Support Staff. 

Please visit the UCL HR Page for more information on these positions 1584538