UCL DEPARTMENT OF BIOCHEMICAL ENGINEERING

Biochemical Engineering

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Dr. Qiang Li

Post-doctoral Research Associate

Phone:+44 (0)20 7679 3247 (Internal 33247) Fax: +44 (0)20 7916 3943 qiang.li@ucl.ac.uk

Education

•    PhD (microbiology and bioprocessing), University of Strathclyde (Glasgow)

•    BSc Eng (Chemical), Tsinghua University (Beijing)

Research Interests

Qiang’s research interests are in the area of bioprocessing. He has intensive experience in various types and scales of fermentations and fermentation development. He is now heading of IMRC work in the department on ultra scale down of recombinant E. coli fermentation and links between upstream and downstream bioprocessing. His most recent work focuses on the product quality attributes during mAb bioprocessing using ultra scale down models. In the past, he had spent three years investigating the events of oxidative stress in fungal fermentations for his PhD at University of Strathclyde before moved to Oxford University, where he spent another two years as a postdoctoral researcher working on the bioprocessing of ligonocellulosic material to generate high value products employing strict anaerobes.

Selected publications

Li Q, O’Donnell A, Bai Z, Hoskisson P, Harvey L, McNeil B. Oxidative stress in fungal fermentation processes: the roles of alternative respiration. Biotechnology Letters. 2011; 33(3):457-67.

Li Q, Siles Lopez J, Thompson I. Succinic acid production from orange peel and wheat straw by batch fermentations of Fibrobacter succinogenes S85. Applied Microbiology and Biotechnology. 2010; 88(3): 671-678.

Siles Lopez J, Li Q and Thompson I. Biorefinery of orange peel. Critical Review in Biotechnology. 2010; 30(1): 63-69.

Li Q, Harvey LM, McNeil B. Oxidative stress in industrial fungi. Critical Review in Biotechnology. 2009; 29(3):199-213.

Li Q, Abrashev R, Harvey LM, McNeil B. Oxidative stress associated impairment of glucose and ammonia metabolism in filamentous fungus, Aspergillus niger B1-D. Mycological Research. 2008; 112(9): 1049-1055.

Li Q, Harvey LM, McNeil B. The effects of elevated process temperature on the occurrence and removal of protein carbonyls in the filamentous fungus, Aspergillus niger B1-D. Process Biochemistry. 2008; 43(8): 877-881.

Li Q, Harvey LM, McNeil B. Oxygen enrichment effects on protein oxidation, proteolytic activity and the energy status of submerged batch cultures of Aspergillus niger B1-D. Process Biochemistry. 2008; 43(3): 238-243.

Li Q, McNeil B, Harvey LM. Adaptive response to oxidative stress in the filamentous fungus Aspergillus niger B1-D. Free Radical Biology and Medicine. 2008; 44(3): 394-402.

Li Q, Harvey LM, McNeil B. The effects of bioprocess parameters on extracellular proteases in a recombinant Aspergillus niger B1-D. Applied Microbiology and Biotechnology. 2008; 78(2): 333-341.

Li Q, Harvey LM, McNeil B. Native and heterologous protein oxidation and subsequent degradation in a recombinant filamentous fungus Aspergillus niger B1-D. Microbial Cell Factory. 2006; 5(1): P6.

Liu H, Li Q, Liu D and Zhong JJ. Impact of hyperosmotic condition on cell physiology and metabolic flux distribution of Candida krusei. Biochemical Engeering Journal. 2006; 28(1): 92-98.

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