UCL DEPARTMENT OF BIOCHEMICAL ENGINEERING

Biochemical Engineering

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Brian O'Sullivan

Manager, Microscale Bioprocessing
Phone:+44 (0)20 7679 3246
b.osullivan@ucl.ac.uk

Education

PhD (Chemistry) University of Exeter,
MSc (Chemistry) University College, Cork, National University of Ireland
Professional Appointments, Honours and Awards
Honorary Lecturer, 2011
Deputy Departmental Safety Officer

Research Interests

Brian’s research interests lie in the area of microfluidics – the study of flows in very small (< 1 mm) channel networks, and the exploitation of the unusual fluid properties found at that scale. 
He has extensive experience in the design and fabrication of microfluidic devices in glass and polymers, for applications in chemistry, chemical engineering and now, biochemical engineering.
He currently provides technical support for the Microfluidics Group within the Department, as well as pursuing his own research interest in developing an integrated chemo-enzymatic reactor for the generation of commercially useful compounds

Teaching and Training Activities

In addition to general training in microfluidic fabrication techniques and applications, Brian supplies practical classes and lectures for:

“Emerging Technologies” (BENGGP27)
“Bioprocessing Microfluidics” (BENGM027)

Selected Publications

Brian O'Sullivan, Homam Al-Bahrani, James Lawrence, Maria Campos, Armando Cázares, Frank Baganz, Roland Wohlgemuth, Helen C. Hailes,

Nicolas Szita “Modular microfluidic reactor and inline filtration system for the biocatalytic synthesis of chiral metabolites” Journal of Molecular Catalysis B: Enzymatic (2012), 77, 1.

Chen Z., Bown M.R., O’Sullivan B., MacInnes J.M., Allen R.W.K., Mulder M.,Blom M., van’t Oever R.; “Performance analysis of a folding flow micromixer” Microfluid Nanofluid (2009), 6, 763–774

Salim, Malinda; Mishra, Gautam; Fowler, Gregory J. S.; O'Sullivan, Brian; Wright, Phillip C.; McArthur, Sally L.;  “Non-fouling microfluidic chip produced by radio frequency tetraglyme plasma deposition”  Lab on a Chip  (2007),  7(4),  523-525

Salim, Malinda; O'Sullivan, Brian; McArthur, Sally L.; Wright, Phillip C. ; Characterization of fibrinogen adsorption onto glass microcapillary surfaces by ELISA. Lab on a Chip  (2007),  7(1),  64-70. 

Allen, Ray W. K.; O'Sullivan, B.; Chen, Z.; Goodrich, P.; Birbeck, J.; MacInnes, J. M.; “A microchannel device for studying chemical kinetics in ionic liquid solutions.” Abstracts of Papers, 231st ACS National Meeting, Atlanta, GA, United States, March 26-30, 2006  (2006)

Haswell S.J., Middleton R.J., O'Sullivan B., Skelton V., Watts P., Styring P. “The application of micro reactors to synthetic chemistry”: Chem. Commun.; (2001), 391

Haswell, S.J., O’Sullivan, B., Styring, P.: “Kumada-Corriu reactions in a pressure-driven microflow reactor”: Lab on a Chip; (2001), 164

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