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UCL Antimicrobial Resistance

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Sean Nair

Sean Nair's research is focused in two main areas: 

  • The interactions of bacteria with host cells in health and disease where his primary focus is on the mechanisms by which staphylococci/MRSA, and other hospital-acquired pathogens such as enterococci (VRE) cause disease. 
  • The development of novel antimicrobial strategies to combat infections. These strategies currently include the use of antisense and aptamer technologies, development of new light-activated antimicrobial agents and the identification of bacterial genes coding for potential novel therapeutic targets.

Dr Sean Nair

Dr Sean Nair

Address

-
256 Grays Inn Road
London
London
WC1X 8LD

Appointments

  • Reader in Cellular Microbiology
    Microbial Diseases
    Eastman Dental Institute

Joined UCL

1991-05-01

Research Interests

Sean Nair's research is focused in two main areas:
(i) The interactions of bacteria with host cells in health and disease where his primary focus is on the mechanisms by which staphylococci/MRSA, and other hospital-acquired pathogens such as enterococci (VRE) cause disease.
(ii) The development of novel antimicrobial strategies to combat infections. These strategies currently include the use of antisense and aptamer technologies, development of new light-activated antimicrobial agents and the identification of bacterial genes coding for potential novel therapeutic targets.

Research Opportunities

In Sean's lab there are currently projects available to investigate aspects of bacterial virulence, antimicrobial resistance and the development of novel antimicrobial agents. Potential MSc and PhD students and individuals suitable for personal fellowships should contact Sean directly.



Award year Qualification Institution
1991 PhD
Doctor of Philosophy
Biochemistry
University of Wales, College of Cardiff
1987 BSc Hons
Bachelor of Science (Honours)
Biochemistry
To be updated

Sean graduated with a BSc Honours degree in Biochemistry from Cardiff University in 1988 and completed his PhD in 1992.He had a number of postdoctoral positions involving research on both human cells and bacteria before being appointed to a lectureship in 1996. He was promoted to Senior Lecturer at UCL in 1999 and then to Reader in 2006. Sean is currently the Head of Microbial Diseases and editor for BMC Microbiology and the Journal of Medical Microbiology.

Keywords

2D Difference Gel Electrophoresis|*|3D cell culture|*|Anti-sense and morpholino approaches|*|Antibiotic resistance|*|Antibody assays|*|Atomic force microscopy|*|BAC recombination and related transgene approaches|*|Bacteriology|*|Biofilms|*|Bioinformatic analysis|*|Bone infections|*|Cell adhesion|*|Cell culture|*|Clinical Research|*|Clinical trials|*|Computational modeling|*|Confocal microscopy|*|Cytokine assays|*|Dental caries|*|Enterococci|*|FACS|*|Fluorescence Resonance Energy Transfer (FRET)|*|Fluorescence microscopy techniques|*|Gene expression|*|Gene expression profiling - single cell|*|Gene expression profiling - tissue level|*|Gene targeting|*|Genetic manipulation (including knockout/knockin)|*|Genetic screens|*|Genetically encoded reporters/indicators|*|Genetics|*|Genomewide association analysis|*|Genomic analyses|*|Genomics|*|Gingivitis|*|Hospital-aquired infections|*|Image analysis|*|Infection|*|Infectious disease|*|Infectious diseases|*|Light microscopic techniques|*|MALDI-TOF MS|*|Mass spectrometry|*|Microarrays|*|Models of disease|*|Nanoparticles|*|Oral|*|Oral microbiology|*|Periodontal diseases|*|Proteomics|*|QPCR|*|RNA interference|*|Recombinant protein expression|*|Staphylococcus aureus