Guest Speaker Milka Sarris

"Navigating in Tissue Mazes: Chemoattractant Interpretation in Complex Environments"

Event Host : Buzz Baum

Speaker's affiliation Department of Physiology, Development and Neuroscience, University of Cambridge

Monday, 12 October, 2015 - 16:00
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Review in Frontiers for Genetics for the Ketteler Lab

"A new age in functional genomics using CRISPR/Cas9 in arrayed library screening"

Publication Link

Read more about the Robin Ketteler Research Group

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Group Leader Spotlight

Gene expression dynamics

Gene expression dynamics Despite the generation of transcriptional differences between nearby related cells being the basis of most differentiation and disease, our standard measures of RNA synthesis do not register the origins of these differences. Although useful for a preliminary rough sorting of genes to context, the widespread techniques of Northern blotting, microarrays, RT-PCR and RNA-Seq measure bulk RNA levels from homogenous population extracts. These approaches lose dynamic information from individual cells, and give the impression transcription is a continuous smooth process. The reality is that transcription is irregular, with strong variable duration periods of activity,...

About Us

The Medical Research Council Laboratory for Molecular Cell Biology (MRC LMCB) opened in 1993 on the Gower Street Campus of UCL. In 2013 the MRC LMCB became an MRC-UCL University Unit and Division within the Faculty of Life Sciences under the Directorship of Professor Mark Marsh

Our Vision

The scientific aims of the LMCB & Cell Biology Unit is to provide a molecular understanding of cell behaviour through discovery-based research. Cell biology is one of the most exciting and important areas of biomedical research and is likely to remain so for the foreseeable future.

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UCL enjoys a beautiful location at the heart of London. Studying and working at UCL will provide you with the opportunity to explore the best cultural and social events that makes London one of the most vibrant and multicultural cities in the world.