Cell signaling and autophagy
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The Ketteler lab is interested in the regulation of cancer signaling pathways. We employ high-throughput screening and novel biomolecular tools to investigate growth factor signaling cascades and to identify therapeutic targets for anti-cancer strategies. The two main research projects are:
1) Identification of novel Grb2 mediated signaling pathways
The small adaptor molecule Grb2 links growth receptor signaling to intracellular signal transduction cascades such as the MAP kinase pathway. In...